From Cognitive Screening to Dissecting the Mind Translational and Basic Neuropsychological Studies After Stroke



Time: 4:30-5:30 p.m., July 17, 2013

Venue: Medical Science Building, C301

Reporter: Glyn Humphreys, Department of Experimental Psychology, Oxford University, Oxford OX1 3UD
Glyn Humphreys is a cognitive neuropsychologist with research interests covering: the diagnosis and management of cognitive problems after brain injury, visual attention, perception, language and the control of action, social cognition. He has published over 500 papers in international journals and 16 books. He has been awarded the Spearman Medal, the Prize for Cognitive Psychology (twice), and the President’s Award of the British Psychological Society, the Donald Broadbent Prize from the European Society for Cognitive Psychology, a Humboldt Fellowship, the Leibniz Professorship, a Special Professorship of the Chinese Academy of Sciences and a Distinguished Professorship by the University of Hong Kong. He is a Fellow of the Association for Psychological Sciences, the Royal Society of Medicine, the Academy of Social Sciences and the British Academy. He has edited the Quarterly Journal of Experimental Psychology, Visual Cognition (founding Editor) and the Journal of Experimental Psychology: Human Perception and Performance. He is currently Watts Professor of Experimental Psychology at the University of Oxford.
In this talk I will provide an overview of research in the cognitive neuropsychology centre at Oxford University. The centre has, at its heart, the routine cognitive screening of stroke patients which then gives rise to a spread of both translational and basic research projects. Our translational work has involved developing an embedded series of screening tests which are designed to maximise inclusion by minimising contaminating effects of problems such as aphasia and neglect on stroke patients. I will report on an evaluation of our tests compared with competitors in the field (e.g., the MOCA) demonstrate the use of the test in clinical decision making. In addition, we have been able to analyse the associations between the sites of brain lesion in the patients and the nature of the cognitive deficit, and to use lesion analyses to help predict which patients show improvements at 6 months and which continue to show clinical problems. Moving on from cognitive screening and lesion-symptom mapping, we continue to analyse patients admitted into studies based on either their brain lesion or the nature of the functional deficit. I will illustrate this through an analysis of a patient with the first-ever reported deficit in exact number identification from audition and I discuss the implications for understanding auditory access to magnitude. Overall the studies demonstrate the continuing importance of neuropsychology for current day cognitive neuroscience.


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