Neuroscience CommunityBACK

Hong, Bo

Associate Dean and Principle Investigator,  School of Medicine, Tsinghua University

Office Phone: +86-10-62795985
Fax: +86-10-62792416
[Research Focus] 1. Speech network analysis of human brain
2. Complex sound processing in rat midbrain
3. Brain computer interfaces
[Me & Science] We may take it for granted of our ability of speaking and listening in daily communication. Surprisingly, we know very little about the brain mechanism of this magic cycle of speech production and perception. Millions of people are suffering from hearing and communication disorder, hoping for innovative treatment and rehabilitation. In my lab, we are searching for the neural code of sound and speech representation in the brain. We look at very precise firing of single neurons in the rat brain, to identify neural circuits accounting for the processing of complex sounds. Meanwhile, collaborating with neurosurgeons, the speech-processing network of human brain is investigated by checking the population activity from the surface of patients’ brain. Putting these puzzle pieces together, a picture of speaking and listening brain is emerging from the massive neural data. Besides helping patients, the neural circuits and codes that we are finding will surely be a crucial hint of developing a smarter speech recognition system, like Siri on your cell phone.
[Education & Experience] 2005-present     Associate Professor, Dept. of Biomedical Engineering, School of Medicine, Tsinghua University 
2004-2005       Visiting Faculty, Dept. of Biomedical Engineering, School of Medicine, Johns Hopkins University 
2001-2005       Assistant Professor, Dept. of Biomedical Engineering, School of Medicine, Tsinghua University 
1996-2001       Ph.D. Biomedical Engineering, Tsinghua University 
1999-2000       Research Assistant, Dept. of Psychology, Chinese University of Hong Kong 
1991-1996       B.S. Biomedical Engineering, Tsinghua University
[Selected Publications]

1. Zhang D, Song H Xu R, Zhou W, Ling Z*, Hong B*. Toward a minimally invasive brain-computer interface using a single subdural channel: A visual speller study. Neuroimage 71:30-41, 2013.

2.Qian T, Zhou W, Ling Z, Gao S, Liu H, Hong B*. Fast presurgical functional mapping using task-related intracranial high gamma activity. Journal of Neurosurgery, 2013 (Accepted with Editorial)

3.Xu H, Zhang D, Ouyang M, Hong B*. Employing an active mental task to enhance the performance of auditory attention-based brain-computer interfaces.Clinical Neurophysiology, 124(1):83-90, 2013

4.Xie K, Yan Y, Fang X, Gao S, Hong B*. Characteristics and classification of hippocampal theta rhythm induced by passive translational displacement. Neuroscience Letters, 515(1):18-22, 2012

5.Zhang D, Song H, Xu H, Gao S, Hong B*. An online N200 speller: integrating the spatial profile for the detection of the non-control state. Journal of Neural Engineering,9(2):026016, 2012

6.Zhao L, Liu Y, Shen L, Feng L, Hong B*. Stimulus-specific adaptation and its dynamics in the inferior colliculus of rat. Neuroscience. 181:163-174, 2011

7.Guo J, Gao S, Hong B*. An auditory brain computer interface using active mental response. IEEE Trans. Neural Systems and Rehabilitation Engineering,18(3):230-5, 2010. (Cover Story)

8.Liu T, Goldberg L, Gao S, Hong B*. An online brain-computer interface using non-flashing visual evoked potentials. Journal of Neural Engineering, 7(3):036003. 2010

9.Hong B*, Guo F, Liu T, Gao XR, Gao SK. N200-speller using motion-onset visual response. Clinical Neurophysiology, 120:1658–1666, 2009

10.Guo F, Hong B*, Gao XR, Gao SK. Brain computer interface using motion-onset visual evoked potential. Journal of Neural Engineering, 5:477–485, 2008

11.Lou B, Hong B*, Gao XR, Gao SK. Bipolar electrode selection for motor imagery based brain-computer interface. Journal of Neural Engineering, 5:342–349, 2008

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