Neuroscience CommunityBACK

Guo,Zengcai
​Assistant Professor, Medical School, Tsinghua University
Office Phone: +86-10-62792669 
Email: zengcai.guo@biomed.tsinghua.edu.cn
[Research Focus] 1. Perceptual decision making
2. Working memory
3. Neural circuits
[Me & Science] My first encounter with neuroscience was as an applied math graduate student. I was amazed by the rich behavioral repertoire of the roundworm C. elegans, which has a small nervous system of only 302 neurons. Just a few dozen motor neurons are sufficient to coordinate the worm to move elegantly, while a few sensory and interneurons guide the animal to track chemical gradients. The mammalian brain, with millions to billions of neurons, is far more complicated and capable than a small nematode. High-level cognitive functions such as working memory, decision-making and consciousness are the biggest mysteries in the complicated nervous system. The long-term goal of our research is to understand how neural circuits in the mammalian brain implement these cognitive functions. To do so, we integrate optogenetics, multi-electrode recordings, two-photon optical imaging, and behavioral measurements to probe the neural dynamics underlying perceptual decision-making behaviors.
[Education & Experience] 2015-present, Assistant professor, Medical School, Tsinghua University
2010-2015, Postdoctoral Associate, HHMI’s Janelia Research Campus
2004-2010, PhD, Applied Mathematics, Harvard University
2002-2004, MS, Solid Mechanics, Tsinghua University
1998-2002, BS, Engineering Mechanics, Tsinghua University
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